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Darryn Willoughby
Darryn Willoughby

Darryn S. Willoughby, Ph.D.

Associate Professor, Health, Human Performance, and Recreation
Director, Exercise and Biochemical Nutrition Laboratory

Baylor University
College of Health & Human Sciences, HHPR
One Bear Place #97313
Waco, Texas 76798-7313
Office: Rena Marrs McLean Gymnasium, 123
Lab: Rena Marrs McLean Gymansiun, 120
Phone: 254-710-3504
Fax: 254-710-3527
Email: Darryn_Willoughby@baylor.edu

Degrees:
Ph.D. Texas A&M University, 1993; Specialization in neuromuscular exercise physiology and biochemistry, sub-specialization in nutritional biochemistry: Dissertation: Clenbuterol and Exercise: Effects of a Beta 2-Adrenoceptor Agonist on Locomotor Endurance Capacity and Muscular Force Production.
M.Ed. Tarleton State University, 1989; Health and Fitness; Thesis title: Comparison of Isotonic Free Weights and Omnikinetic Exercise Machines on Strength.
B.S. Tarleton State University, 1986; Health and Fitness.

Professional Interests:
Molecular Physiology and Biochemistry of Exercise and Nutrition
Cellular and Molecular Physiology of Muscle
Exercise and Sport Nutrition
Human Nutrition, Metabolism, and Weight Management
Neuromuscular Exercise Physiology
Strength Training and Sport Conditioning

Research Interests:
Effects of Exercise Training and Nutritional Intervention on the Physiological, Biochemical, and Molecular Mechanisms Regulating Skeletal Muscle Strength, Hypertrophy, and Atrophy in Athletes, Aging, and other Special Populations

Selected Refereed Publications (last 4 years):

Buford, T., Cooke, M., Shelmadine, B., Hudson, G., Redd, L., & Willoughby, D.S. Differential gene expression of FoxO1, ID1, and ID3 between young and older men and associations with muscle mass and function. Aging Clinical and Experimental Research. 23:170-74.

Bunn, J., & Willoughby, D. S. Effects of 28 days of protein and amino acid supplementation and ankle immobilization on gastrocnemius muscle mass and strength and atrophy-
and apoptosis-related gene expression in males. Journal of Nutrition and Metabolism. 2011.

Buford, T., Cooke, M., Shelmadine, B., Hudson, G., Redd, L., & Willoughby, D.S. Biomarkers of sarcopenia from skeletal muscle biopsies in men. Gerontologist. 50:45-55, 2010.


Willoughby DS, Boucher T, Reid J, Skelton G, Clark M. Effects of seven days of arginine-alpha-ketoglutarate supplementation on blood flow, plasma L-arginine, nitric oxide metabolites, and asymmetric dimethyl arginine after resistance exercise. International Journal of Sport Nutrition and Exercise Metabolism. 21:291-99, 2011.

 

Beavers K, Serra M, Beavers D, Hudson G, Willoughby DS.  The lipid lowering effects of four weeks of daily soymilk or dairy milk ingestion in a postmenopausal female population.  Journal of Medicinal Food. 13:650-56, 2010.

 

Beavers K, Serra, M, Beavers D, Cooke M, Willoughby DS.  Soy and the Exercise Induced Inflammatory Response in Postmenopausal Women.  Applied Physiology, Nutrition, and Metabolism. 35:261–269, 2010.

 

Buford T, Cooke M, Manini T, Leeuwenburgh C, Willoughby DS. Effects of age and sedentary lifestyle on skeletal muscle NF-kappaB signaling in men. Journal of Gerontology A: Biological Science and Medical Science. 65:532-37, 2010. 

 

Kerksick C, Kreider R, Willoughby DS. Intramuscular adaptations to eccentric exercise and antioxidant supplementation. Amino Acids. 39:219-32, 2010.

 

Beavers K, Serra M, Beavers D, Cooke M, Willoughby DS.  Soymilk supplementation does not alter plasma markers of inflammation and oxidative stress in postmenopausal women. Nutrition Research. 29:616-22, 2009.

 

Buford T, Cooke M, Shelmadine B, Hudson G, Redd L, Willoughby DS. Effects of eccentric treadmill exercise on inflammatory gene expression in human skeletal muscle. Applied Physiology, Nutrition, and Metabolism. 34:745-53, 2009.

 

Wilborn C, Taylor L, Greenwood M, Kreider R, Willoughby DS. Effects of different intensities of resistance exercise on regulators of myogenesis. Journal of Strength and Conditioning Research. 23:2179-87, 2009.

 

Buford T, Cooke M, Redd L, Hudson G, Shelmadine B, Curts C, Willoughby DS. Dietary protease supplementation attenuates eccentric-exercise induced force production decrements by augmenting leukocyte activity and systemic inflammation. Medicine and Science in Sports and Exercise. 41:1908-14, 2009.

 

Buford T, Cooke M, Willoughby DS. Resistance exercise in older women up-regulates expression of numerous inflammation-related genes within skeletal muscle. European Journal of Applied Physiology. 2009.

 

Shelmadine B, Buford T, Hudson G, Redd L, Cooke M, Leutholtz B, Willoughby DS. Effects of 28 days of NO-Shotgun supplementation on body composition, muscle strength and mass, markers of satellite cell activation, and clinical safety markers in males. Journal of the International Society of Sports Nutrition. 6:16, 2009.

 

Spillane M, Schoch R, Cooke M, Harvey T, Greenwood M, Kreider R, Willoughby DS. The effects of creatine ethyl ester supplementation combined with heavy resistance training on body composition, muscle performance, and serum and muscle creatine levels. Journal of the International Society of Sports Nutrition. 6:6, 2009.

 

Jitomir J, Nassar E, Culbertson J, Moreillon J, Buford T, Hudson G, Cooke M, Kreider R, Willoughby DS. The acute effects of the thermogenic supplement Meltdown on energy expenditure, fat oxidation, and hemodynamic responses in young, healthy males. Journal of the International Society of Sports Nutrition. 5:23, 2008.

 

Jitomir J, Willoughby DS. Leucine for the retention of lean mass on a hypocaloric diet. Journal of Medicinal Foods. 11:606-609, 2008.

 

Kerksick C, Taylor L, Bouw B, Harvey A, Willoughby DS. The protective effect of estrogen against oxidative stress, inflammation, apoptosis, and exercise-induced muscle injury in males and females. Medicine and Science in Sports and Exercise. 40:1772-80, 2008.

 

Roberts M, Taylor L, Wismann J, Wilborn C, Kreider R, Willoughby DS. Effects of ingesting JavaFit™ Energy Extreme functional coffee on aerobic and anaerobic fitness markers in college-aged caffeine consumers. Journal of the International Society of Sports Nutrition. 4:21, 2007.

 

Roberts M, Iosia M, Kerksick C, Taylor L, Campbell B, Wilborn C, Harvey T, Cooke M, Rasmussen C, Greenwood M, Wilson R, Jitomir J, Kreider R, Willoughby DS. Effects of arachidonic acid supplementation on training adaptations in resistance-trained males. Journal of the International Society of Sports Nutrition. 4:21, 2007.

 

Nassar E, Mulligan C, Taylor L, Kerksick C, Galbreath M, Greenwood M, Kreider R, Willoughby DS. Effects of Prophylactic N-Acetyl-5-methoxytryptamine (Melatonin) Supplementation and Resistance Exercise on Serum Growth Hormone Levels and Other Hormones of the HPA Axis in Young Males and Females. Journal of the International Society of Sports Nutrition. 4:14, 2007.

 

Rohle D, Wilborn C, Taylor L, Mulligan C, Willoughby DS. Effects of Eight Weeks of Aromatase Inhibition Using the Nutritional Supplement 6-OXO (androst-4-ene-3,6,17-trione): Effects on Serum Hormone Profiles and Clinical Safety Markers in Resistance-Trained, Eugonadal Males. Journal of the International Society of Sports Nutrition. 4:13, 2007.

 

Taylor L, Wilborn C, Harvey T, Wismann, J, Willoughby DS. Acute effects of ingesting Java FitTM energy extreme functional coffee on resting energy expenditure and hemodynamic responses in male and female coffee drinkers. Journal of the International Society of Sports Nutrition. 4:10, 2007.

Willoughby DS, Wilborn C, Taylor L, Campbell B. Eight weeks of aromatase inhibition using the nutritional supplement Novedex XT: Effects on serum steroid hormones, body composition, and clinical safety markers in young, eugonadal males. International Journal of Sports Nutrition and Exercise Metabolism. 17(1), 92-108, 2007.

Willoughby D S, Stout J, Wilborn C. Effects of heavy resistance training and timed ingestion of a protein and amino acid supplementation on muscle strength and mass and muscle anabolism. Amino Acids. 32(4), 467-478, 2007.

Professional Honors:
Fellow, International Society of Sports Nutrition, (ISSN) 2003.
Fellow, American Society of Exercise Physiologists, (ASEP) 2001.
Fellow, American College of Sports Medicine, (ACSM) 1998.

Professional Certifications:
Certified Sport Nutritionist (ISSN)
Certified Exercise Physiologist (ASEP)
Certified Nutrition Specialist (AFPA)
Certified Strength and Conditioning Specialist (NSCA)

Professional Affiliations:
American College of Sports Medicine (ACSM)
American Physiological Society (APS)
Federation of the American Societies of Experimental Biology (FASEB)
International Society of Sports Nutrition (ISSN)
National Strength and Conditioning Association (NSCA)
Texas Chapter of the American College of Sports Medicine (TACSM)

Courses Taught:
Undergraduate
Exercise Physiology
Exercise Physiology Laboratory
Exercise Biochemistry
Strength Training and Conditioning
Exercise Testing and Prescription
Exercise Pharmacology
Human Anatomical Kinesiology

Graduate
Nutritional Biochemistry
Molecular Response to Exercise
Neuromuscular Exercise Physiology
Muscle Physiology and Biochemistry
Exercise Endocrinology
Cardiopulmonary Exercise Physiology
Clinical Exercise Testing and Prescription
Exercise Physiology Laboratory
Strength Training and Conditioning
Exercise Biochemistry & Endocrinology
Sports Nutrition
Laboratory Techniques in Exercise and Molecular Physiology