Vascular Disrupting Agents
Dr. Pinney is a professor of chemistry at Baylor University and is also a member of The Institute of Biomedical Studies. He has extensive training in synthetic organic chemistry and additional research expertise in areas that encompass medicinal chemistry and biochemistry.
He and colleague, Dr. Mary Lynn Trawick, associate professor of chemistry and biochemistry, recently received a $1.46 million grant from the National Institutes of Health to research and test new compounds that could help fight cancerous tumors.
Well-established research projects in the Pinney Research Laboratory focus on understanding the salient features of small molecule molecular recognition of selected bioreceptors including proteins and enzymes. Current research efforts center primarily on small-molecule, vascular disrupting agents (VDAs) to selectively starve tumors of nutrients and oxygen, inhibitors of tubulin assembly, and inhibitors of cathepsin L to limit or arrest cancer metastasis.
Nearly all of these projects are collaborative in nature between the Pinney Group (synthetic and medicinal chemistry) and Trawick Group (biochemistry and cell biology) both at Baylor University.
The Pinney Research Group is typically composed of approximately fifteen members including graduate and undergraduate students, postdoctoral research associates, and a research administrative associate. Each summer, Dr. Pinney also mentors one or two high school students through the Baylor University High School Summer Science Research Program.
Dr. Pinney is the author of over 40 peer reviewed articles and book chapters and is a co-inventor on twenty issued patents along with several pending patent applications. Research funding is currently provided by grants from The Cancer Prevention and Research Institute of Texas (CPRIT) and The National Institutes of Health (NIH).
Dr. Pinney recently completed an appointment (2010-2012) as a member of the Steering Committee for the "Chemistry in Cancer Research" (CICR) Working Group associated with the American Association of Cancer Research (AACR) and was honored to receive the "The Cornelia Marschall Smith Professor of the Year Award" at Baylor University in 2006.
Dr. Pinney joined the faculty in the department of chemistry and biochemistry at Baylor University in 1993 having completed his Ph.D. at The University of Illinois followed by a NIH postdoctoral research fellowship at the University of South Carolina.
To interview Dr. Pinney, contact Tonya B. Lewis, (254) 710-6275, or the Office of Media Communications at (254) 710-1961.