Postdoctoral Fellow, Virginia Institute for Psychiatric and Behavioral Genetics & Department of Psychiatry, Virginia Commonwealth University, 2007-2010
Postdoctoral Fellow, Midwest Alcohol Research Center & Department of Psychiatry, Washington University School of Medicine in St. Louis, 2006-2007
Postdoctoral Fellow, Center for Developmental Science, University of North Carolina at Chapel Hill, 2004-2006
Ph.D., Developmental Psychology, Columbia University, 2004
M.S., Applied Statistics, Columbia University, 2003
B.A., Psychology, Pacific Lutheran University, 1992
Dr. Latendresse joined the department in 2013 following three years on faculty at the Virginia Institute for Psychiatric and Behavioral Genetics within the Department of Psychiatry at Virginia Commonwealth University. After earning advanced degrees in developmental psychology (Ph.D.) and applied statistics (M.S.) at Columbia University in New York City, Dr. Latendresse received postdoctoral training in developmental science at the Center for Developmental Science at the University of North Carolina at Chapel Hill, and in molecular and behavioral genetics at the Washington University School of Medicine in St. Louis and the Virginia Institute for Psychiatric and Behavioral Genetics. In 2010, he was appointed to the editorial board for the Child and Neurodevelopmental Psychiatry section of Frontiers in Psychiatry. Dr. Latendresse also serves the field via ad hoc manuscript reviews, external grant reviews, and panel reviews for the scientific meetings of the professional associations and societies to which he belongs.
General Interests: developmental psychopathology, risk/resilience, parental socialization, social and environmental determinants of health, behavioral genetics, epigenetics, psychological measurement, and applied statistics
My program of research broadly focuses on delineating etiological pathways and mechanisms involved in the development of alcohol use/problems/disorder and related behavioral phenotypes (e.g., internalizing and externalizing symptoms). I am particularly interested in the role that parents play in exacerbating risk and/or promoting resilience in the behavioral development of their offspring via socialization practices, genetic transmission, and the complex associations that exist among these and other important contextual (e.g., environmental influences, treatment effects) and biological factors (e.g., epigenetic processes, chromosomal instability). In my lab, we address these issues using data from a large number of existing and on-going longitudinal studies.
Beyond seeking to identify critical biopsychosocial mechanisms in the development of behaviors, I also conduct research aimed at improving the precision with which these constructs are measured. With funding from the National Institute for Alcohol Abuse and Alcoholism, we are currently utilizing integrative data analytic techniques to develop commensurate (i.e., invariant) phenotypic constructs for various dimensions of externalizing behavior (e.g., aggression, delinquency, intrusiveness, and attention deficit/hyperactivity) using data pooled across a number of (a) independent community-based samples, (b) psychometric instruments, and (c) developmental periods. Ensuing phenotypes will then serve as the units of measurement from which generalized trajectories of risk can be derived, with corresponding reductions in measurement error expected to yield more reliable and valid characterizations of the development of behavior (both quantitative and qualitative), and an improved ability to identify critical early environmental and genetic antecedents of high-risk trajectories, as well as their alcohol-related sequelae in adulthood. Importantly, use of this approach will allow us to directly assess the extent to which these integrative data analysis procedures replicate, extend, and/or improve upon traditional single-study longitudinal analyses, and whether potential sources of between-study heterogeneity further inform on findings derived from data for which measurement non-invariance has been addressed across pooled samples.
* indicates student co-author
Luthar, S. S., & Latendresse, S. J.(2005). Comparable "risks" at the socioeconomic extremes: Pre-adolescents perceptions of parenting. Development and Psychopathology, 17, 207-230.
Luthar, S. S., & Latendresse, S. J.(2005). Children of the affluent: Challenges to well-being. Current Directions in Psychological Science, 14, 49-53.
Farmer, T. W., Dadisman, K., Latendresse, S. J., Thompson, J., Irvin, M. J., & Zhang, L. (2006, August 30). Educating out and giving back: Adults’ conceptions of successful outcomes of African-American high school students from impoverished rural communities. Journal of Research in Rural Education, 21(10), http://www.umaine.edu/jrre/21-10.htm
Latendresse, S. J., Rose, R. J., Viken, R. J., Pulkkinen, L., Kaprio, J., & Dick, D. M. (2008). Parenting mechanisms in links between parents’ and adolescents’ alcohol use behaviors. Alcoholism: Clinical and Experimental Research, 32, 322-330. doi: 10.1111/j.1530-0277.2007.00583.x
Latendresse, S. J., Rose, R. J., Viken, R. J., Pulkkinen, L., Kaprio, J., & Dick, D. M. (2009). Parental socialization and adolescents’ alcohol use behaviors: Predictive disparities in parents’ versus adolescents’ perceptions of the parenting environment. Journal of Clinical Child and Adolescent Psychology, 38, 232-244. doi: 10.1080/15374410802698404
Dick, D. M., Latendresse, S. J., Lansford, J. E., Budde, J. P., Goate, A., Dodge, K. A., Pettit, G. S., Bates, J. E. (2009). The role of GABRA2 in trajectories of externalizing behavior across development and evidence of moderation by parental monitoring. Archives of General Psychiatry, 66, 649-657. doi: 10.1001/archgenpsychiatry.2009.48Latendresse, S. J., Rose, R. J., Viken, R. J., Pulkkinen, L., Kaprio, J., & Dick, D. M. (2010). Examining the etiology of associations between perceived parenting and adolescents’ alcohol use: Common genetic and/or environmental liabilities. Journal of Studies on Alcohol and Drugs, 71, 313-325. Latendresse, S. J., Rose, R. J., Viken, R. J., Pulkkinen, L., Kaprio, J., & Dick, D. M. (2010). Examining the etiology of associations between perceived parenting and adolescents’ alcohol use: Common genetic and/or environmental liabilities. Journal of Studies on Alcohol and Drugs, 71, 313-325.
Edwards, A. C., Dodge, K. A., Latendresse, S. J., Lansford, J. E., Bates, J. E., Pettit, G. S., Budde, J. P., Goate, A., & Dick, D. M. (2010). MAOA uVNTR and early parent-to-child aggression interact to influence delinquent behavior. Journal of Child Psychology and Psychiatry, 51, 679-687. doi: 10.1111/j.1469-7610.2009.02196.x
Dick, D. M., Meyers, J. *, Latendresse, S. J., Creemer, H., Lansford, J. E., Pettit, G. S., Bates, J. E., Dodge, K. A., Budde, J., Goate, A., Buitelaar, J. K., Ormel, H., Verhulst, F. C., & Huizink, A. C. (2011). CHRM2, parental monitoring, and adolescent externalizing behavior: Evidence for gene-environment interaction. Psychological Science, 22, 481-489. doi: 10.1177/0956797611403318
Dick, D. M., Latendresse, S. J., & Riley, B. (2011). Incorporating genetics into your studies: A guide for social scientists. Frontiers in Psychiatry, 2:17. doi: 10.3389/fpsyt.2011.00017
Maher, B. S., Vladimirov, V. I., Latendresse, S. J., Thiselton, D., Kang, M., Bigdeli, T. B., Chen, X., Riley, B. P., Hettema, J. M., Dick, D. M., Devlin, B., Ferrell, R. E., Kirillova, G. P., Tarter, R. E., Kendler, K. S., & Vanyukov, M. M. (2011). The AVPR1A gene and substance use disorders: Association, replication and functional evidence. Biological Psychiatry, 70, 519-527. doi: 10.1016/j.biopsych.2011.02.023
Latendresse, S. J., Bates, J. E., Goodnight, J. A., Lansford, J. E., Budde, J. P., Goate, A., Dodge, K. A., Pettit, G. S., & Dick, D. M. (2011). Differential susceptibility to adolescent externalizing trajectories: Examining the interplay between CHRM2 and peer group antisocial behavior. Child Development, 82, 1797-1814. doi: 10.1111/j.1467-8624.2011.01640.x
Petersen, I. T., Bates, J. E., Goodnight, J. A., Dodge, K. A., Lansford, J. E., Pettit, G. S., Latendresse, S. J., & Dick, D. M. (2012). Interaction between serotonin transporter polymorphism (5-HTTLPR) and stressful life events in adolescents’ trajectories of anxious/depressed symptoms. Developmental Psychology, 48, 1463-1475. doi: 10.1037/a0027471
Peterson, R. E. *, Latendresse, S. J., Bartholome, L. T., Warren, C. S., & Raymond, N. C. (2012). Binge eating disorder mediates links between internalizing behaviors and energy intake in obese women. Obesity, 2012, 8 pages. doi: 10.1155/2012/407103
York, T. P., Eaves, L. J., Lichtenstein, P., Neale, M. C., Svensson, A., Latendresse, S. J., Långstöm, N., & Strauss, J. F. (2013).Fetal and maternal genes influence gestational age in a quantitative genetic analysis of 244,000 Swedish births. American Journal of Epidemiology, 178, 543-550. doi: 0.1093/aje/kwt005
Dick, D. M., Aliev, F., Latendresse, S. J., Porjesz, B., Schuckit, M., Hesselbrock, V., Edenberg, H., Nurnberger, Jr., J., Agrawal, A., Bierut, L., Wang, J., Bucholz, K., Kuperman, S., & Kramer, J. (2013). How phenotype and developmental stage affect the genes we find: GABRA2 and impulsivity. Twin Research and Human Genetics, 16, 661-669. doi: 10.1017/thg.2013.20
Dick, D. M., Aliev, F., Latendresse, S. J., Hickman, M., Heron, J., Macleod, J., Joinson, C., Maughan, B., Lewis, G., & Kendler, K. S. (2013).Adolescent alcohol use is predicted by childhood temperament factors before age 5, with mediation through personality and peers. Alcoholism: Clinical and Experimental Research, 37, 2108-2117. doi: 10.1111/acer.12206
Chan, T. W. S. *, Bates, J. E., Lansford, J. E., Dodge, K. A., Pettit, G. S., Dick, D. M., & Latendresse, S. J. (2014). Impulsivity and genetic variants in DRD2 and ANKK1 moderate longitudinal associations between sleep problems and overweight from ages 5 to 11. International Journal of Obesity, 38, 404-410. doi: 10.1038/ijo.2013.123
Dick, D. M., Cho, S. B., Latendresse, S. J., Aliev, F., Nurnberger, Jr., J. I., Edenberg, H., Schuckit, M., Hesselbrock, V., Porjesz, B., Bucholz, K., Wang, J-C., Goate, A., Kramer, J., & Kuperman, S. (2014). Genetic influences on alcohol use across stages of development: GABRA2 and longitudinal trajectories of drunkenness from adolescence to young adulthood. Addiction Biology, 19, 1055-1064. doi: 10.1111/adb.12066
Aliev, F., Latendresse, S. J., Bacanu, S-A., Neale, M. C., & Dick, D. M. (2014). Testing for measured gene-environment interaction: Problems with the use of cross-product terms and a regression model reparameterization solution. Behavior Genetics, 44, 165-181. doi: 10.1007/s10519-014-9642-1
Swann, G., Byck, G. R., Dick, D. M., Aliev, F., Latendresse, S. J., Riley, B., Kertes, D., Sun, C., Salvatore, J. E., Bolland, J., & Mustanski, B. (2014). Effect of OPRM1 and stressful life events on symptoms of major depression in African American adolescents. Journal of Affective Disorders, 162, 12-19. doi: 10.1016/j.jad.2014.03.020
Edwards, A. C., Latendresse, S. J., Heron, J., Cho, S. B., Hickman, M., Lewis, G., Dick, D. M., & Kendler, K. S. (2014). Childhood internalizing symptoms are negatively associated with early adolescent alcohol use. Alcoholism: Clinical and Experimental Research, 38, 1680-1688. doi: 10.1111/acer.12402
Albert, W. D., Belsky, D. W., Crowley, D. M., Williams, B., Sugden, K., Latendresse, S. J., Aliev, F., Riley, B. P., Sun, C., Conduct Problems Prevention Research Group, Dick, D. M., & Dodge, K. R. (2015). Can genetics predict response to complex behavioral interventions? Evidence from a genetic analysis of the Fast Track Randomized Control Trial. Journal of Policy Analysis and Management, 34, 497-518. doi: 10.1002/pam.21811
Roberson-Nay, R., Beadel, J. R., Gorlin, E. I., Latendresse, S. J. & Teachman, B. A. (2015). Exploring the latent class structure of CO2 hypersensitivity using time course trajectories of subjective and respiratory response. Journal of Behavior Therapy and Experimental Psychiatry, 47, 68-76. doi: 10.1016/j.jbtep.2014.10.013
Meagher, B. R., Lehman, J. C., Bias, J. P., Latendresse, S. J., Rowatt, W. C. (2015). Contrasting self-report and consensus ratings of intellectual humility and arrogance. Journal of Research in Personality, 58, 35-45. doi: 10.1016/j.jrp.2015.07.002
Latendresse, S. J., Henry, D., Aggens, S. H., Byck, G. R., Ashbeck, A. W., Bolland, J., Sun, C., Riley, B. P., Mustanski, B., & Dick, D. M. (in press). Dimensionality and genetic correlates of problem behavior in low-income African American adolescents. Journal of Clinical Child and Adolescent Psychology. doi: 10.1080/15374416.2015.1070353
*Goyal, N., Aliev, F., Latendresse, S. J., Kertes, D., Bolland, J., Byck, G. R., Mustanski, B., Salvatore, J. E., & Dick, D. M. (in press). Genes involved in stress response and alcohol use among high-risk African American youth. Substance Abuse.
K01 AA021399, Edwards (PI) 09/12 - 08/17
NIAAA, Role: Consulting Adviser on Developmental Methodology (in kind)
Genetic Influences on Developmental Heterogeneity of Alcohol Use Disorder
P60 MD002256-05, Strauss (PI)
NIMHD Comprehensive Center of Excellence
R01 subproject, York (PI) 05/12 - 04/17
NIMHD, Role: Co-Investigator (in kind)
Racial Differences in Epigenetic Mechanisms of Preterm Birth
R01 DA007031, Dishion (PI) 09/11 - 05/16
NIDA, Role: Co-Investigator
Development, Ecology, and Prevention of Adult Addictive Behavior
K01 AA020333, Latendresse (PI) 04/11 - 3/16
NIAAA, Role: Principal Investigator
Phenotypic Refinement of Externalizing Pathways to Alcohol-related Behaviors
Meredith Hoyland, Luther College
Maddie Larson, University of Washington
Dr. Latendresse is currently accepting applications for Ph.D. students.