Dr. Erika Abel has been a professor at Baylor University since 2011. Prior to that, she was an NIH-supported postdoctoral fellow and then a research professor at the University of Texas MD Anderson Cancer Center, where she studied genetic and environmental factors that contribute to skin and pancreatic cancer risk. She serves on multiple task forces and committees, including the Steering Committee for Women in Science and Engineering and the Prehealth Programs Committee for the College of Arts and Sciences. She has served as a faculty leader on multiple medical mission trips with Baylor Prehealth students. Dr. Abel teaches courses in molecular cell biology, biochemistry, genetics and biological research design.
Academic Interests and Research
Best practices in molecular biological education
Course-based undergraduate research experiences in genetics
Professional Awards/Activities/Grants and Fellowships
Baylor University Leadership and Service
Selected Research Articles
Gueldner, J, Sayes, C, Abel, E*, Bruce E. Emerging Association of the ALDH2*2 Polymorphism with Disease Susceptibility, Journal of Drug Metabolism and Toxicology, 7:2, 2016. *corresponding author
Usenko, CY, Abel, EL, Hopkins, A, Martinez, G, Tijerina, J, Kudela M, Norris, N, Joudeh, L, Bruce, EA. Evaluation of Common Use Brominated Flame Retardant (BFR) Toxicity Using a Zebrafish Embryo Model. Toxics, 43(3), 21, 2016.
Rosenberg M, Abel, E, Garver, W, Osgood, M. Taking the Hassle out of Hasselbalch, Course Source, 3:1-10, 2016.
Usenko, CY, Abel, EL, Kudela, M, Janise, A, Bruce, EA. Comparison of PBDE congeners as inducers of oxidative stress in zebrafish. Environmental Toxicology and Chemistry. 34(5):1154-60, 2015.
Angel JM, Abel EL, Riggs PK, McClellan SA, DiGiovanni J. Fine mapping reveals that promotion susceptibility locus 1 (Psl1) is a compound locus with multiple genes that modify susceptibility to skin tumor development. G3 (Bethesda), Apr 3;4(6):1071-9, 2014.
Bozeman R, Abel EL, Macias E, Cheng T, Beltran L, Digiovanni J. A novel mechanism of skin tumor promotion involving interferon-gamma (IFNγ)/signal transducer and activator of transcription-1 (Stat1) signaling. Mol Carcinog. ePub, ahead of print, 2014.
Abel EL, Boulware S, Fields T, McIvor E, Powell KL, Digiovanni J, Vasquez KM, Macleod MC. Sulforaphane induces phase II detoxication enzymes in mouse skin and prevents mutagenesis induced by a mustard gas analog. Toxicol Appl Pharmacol. 266(3):439-442. 2012
Boulware S, Fields T, McIvor E, Powell KL, Abel EL, Vasquez KM, Macleod MC. 2,6 Dithiopurine, a nucleophilic scavenger, protects against mutagenesis in mouse skin treated in vivo with 2-(chloroethyl) ethyl sulfide, a mustard gas analog. Toxicol Appl Pharmacol. 263:203-209. 2012
Shen J, Abel EL, Riggs PK, Repass J, Hensley SC, Schroeder LJ, Temple A, Chau A, McClellan SA, Rho O, Kiguchi K, Ward MD, Semmes OJ, Person MD, Angel JM, Digiovanni J. Proteomic and pathway analyses reveal a network of inflammatory genes associated with differences in skin tumor promotion susceptibility in DBA/2 and C57BL/6 mice. Carcinogenesis. 33(11):2208-19. 2012.
Surh I, Rundhaug J, Pavone A, Mikulec C, Abel EL, Simper M, Fischer S. The EP1 receptor for prostaglandin E2 promotes the development and progression of malignant murine skin tumors. Molecular Carcinogenesis. 51(7):553-64, 2012.
Abel EL, Bubel JD, Simper MS, Powell L, McClellan SA, Andreeff M, MacLeod MC, DiGiovanni J. Protection against 2-chloroethyl ethyl sulfide (CEES)-induced cytotoxicity in human keratinocytes by an inducer of the glutathione detoxification pathway. Toxicol Appl Pharmacol. 255(2):176-83. 2011
Surh I, Rundhaug J, Pavone A, Mikulec C, Abel EL, Fischer S. Upregulation of the EP1 receptor for prostaglandin E2 promotes tumor progression. Molecular Carcinogenesis. 50(6): 458-60, 2011.
Blando J, Carbajal S, Abel EL, Beltran L, Conti C, Fischer SM, DiGiovanni J. Cooperation between Stat3 and Akt signaling leads to prostate tumor development in transgenic mice. Neoplasia. 13(3):254-65, 2011.
Abel EL, Angel JM, Riggs PK, Langfield L, Lo HH, Person MD, Awasthi YC, Wang LE, Strom SS, Wei Q, Digiovanni J. Evidence That Gsta4 Modifies Susceptibility to Skin Tumor Development in Mice and Humans. J Natl Cancer Inst 102(21):1663-1675. e-Pub 10/2010.
Yasgar A, Shultz J, Z 6 pthou W, Wang H, Huang F, Murphy N, Abel EL, DiGiovanni J, Inglese J, Simeonov A. A High-Throughput 1,536-Well Luminescence Assay for Glutathione S Transferase Activity. Assay Drug Dev Technol 8(2):200-11, 4/2010. PMCID: PMC2864799.
Abel EL, Angel JM, Kiguchi K, DiGiovanni J. Multi-stage chemical carcinogenesis in mouse skin: fundamentals and applications. Nat Protoc 4(9):1350-62, 2009. e-Pub 8/2009.
Chan KS, Sano S, Kataoka K, Abel E, Carbajal S, Beltran L, Clifford J, Peavey M, Shen J, Digiovanni J. Forced expression of a constitutively active form of Stat3 in mouse epidermis enhances malignant progression of skin tumors induced by two-stage carcinogenesis. Oncogene 27(8):1087-94, 2/2008. e-Pub 8/2007.
Riggs PK, Angel JM, Abel EL, DiGiovanni J. Differential gene expression in epidermis of mice sensitive and resistant to phorbol ester skin tumor promotion. Mol Carcinog 44(2):122-36, 10/2005.
Abel EL, Lyon RP, Bammler TK, Verlinde CL, Lau SS, Monks TJ, Eaton DL. Estradiol metabolites as isoform-specific inhibitors of human glutathione S-transferases. Chem Biol Interact 151(1):21-32, 12/2004.
Abel EL, Opp SM, Verlinde CL, Bammler TK, Eaton DL. Characterization of atrazine biotransformation by human and murine glutathione S-transferases. Toxicol Sci 80(2):230-8, 8/2004.
Abel EL, Bammler TK, Eaton DL. Biotransformation of methyl parathion by glutathione Stransferases. Toxicol Sci 79(2):224-32, 6/2004.
Selected Book Chapters
Abel EL, DiGiovanni J. Environmental carcinogenesis. In: The Molecular Basis of Cancer, Fourth Edition. Ed(s) JM Mendelsohn, P Howley, MA Israel, J Gray, CB Thompson. Elsevier
Abel EL, DiGiovanni J. Multistage Carcinogenesis. In: Current Cancer Research: Chemical Carcinogenesis. Ed TM Penning, Springer: New York, NY. 27-50, 2011.
Angel J, Abel E, DiGiovanni J. Genetic Determinants of Cancer Susceptibility. In: Comprehensive Toxicology. 14, 2nd. Ed(s) C McQueen. Elsevier, 371-400, 2010.
Abel EL, DiGiovanni J. Environmental carcinogenesis. In: The Molecular Basis of Cancer, Third Edition. Ed(s) JM Mendelsohn, P Howley, MA Israel, J Gray, CB Thompson. WB Saunders: Philadelphia, 2008. Saunders: Philadelphia, 2015