Dr. Christie M. Sayes’s primary research area of interest is environmental health & safety. Currently, she focuses on exposure characterization along the product value chain. She has more than a decade of experience in the fields of nanotechnology and nanotoxicology and has authored numerous publications, including original research, invited reviews and book chapters.
Sayes has proven abilities in providing technical guidance and leadership to students, technicians, and colleagues; a high aptitude for developing complex research projects; substantial training in nanotechnology-related techniques & instruments; significant experience working independently & collaboratively across disciplines and organizations; and excellent communication skills.
The goal of the research performed in her laboratory is to investigate the fate, transformation, and biological effects of individual particles and particle systems. Her group addresses several fundamental issues relevant to the development safe and effective formulations in biological and environmental applications. These issues include material characterization, exposure kinetics, hazard identification and communication, and mechanistic and molecular analyses.
Sayes CM, Sooresh A, Meissner KE. (2015). Physiological Charactersitics of Two Prototypical Home-Use Consumer Products Containing Engineered Nanomaterials. Environmental & Analytical Toxicology 5(6).
Zeidan E, Kepley C, Sayes CM, Sandros MG. (2015). Surface Plasmon Resonance (SPR): A Label-Free Tool for Nanomedical Applications. Nanomedicine, 10(11):1833-18465.
Hodson L, Sayes CM, Eastlake A, Kuyat S, Geraci C. (under review). Understanding the Nanomaterial Workforce: A Landscape Look at Nanomaterial Manufacturing in the United States. Journal of Occupational and Environmental Hygiene.
Geraci C, Heidel D, Sayes CM, Hodson L, Schulte P, Eastlake A, Brenner S. (2015). Perspectives on the design of safer nanomaterials and manufacturing processes. Journal of Nanoparticle . Research, ahead of print.
Zhang F, Durham P, Sayes CM, Lau BLT, and Bruce ED. (2015). Particle uptake efficiency is significantly affected by type of capping agent and cell line. Journal of Applied Toxicology DOI:10.1002/jat.3138.
Sayes CM, Staats H, Hickey AJ. (2014). Scale of Health: Indices of Safety and Efficacy in the Evolving Environment of Large Biological Datasets. Pharmaceutical Research. 31(9):2256-65.
Sooresh A, Pine M, Sayes CM. (2014). Effects of a novel pesticide-particle conjugate on viability and reactive oxygen species generation in neuronal (PC12) cells. Drug & Chemical Toxicology. 14:1-7.
Sayes CM. (2014). The relationships among structure, activity, and toxicity of engineered nanoparticles, KONA Powder and Particle Journal 31:10.
Romoser AA, Criscitiello MF, Sayes CM. (2014). Engineered nanoparticles induce DNA damage in primary human skin cells, even at low doses, Nano LIFE 4(1):1-13.
Dellinger A, Zhou Z, Connor J, Madhankumar AB, Pamujula S, Sayes CM, Kepley CL. (2013).Application of fullerenes in nanomedicine: an update. Nanomedicine 8(7):1191-1208.
Sayes CM and Ivanov I; (2010) Comparative Study of Predictive Computational Models for Nanoparticle-Induced Cytotoxicity. Risk Analysis, 30(11):1723.