Joon Y. Park, Ph.D.

Joon Y. Park, Ph.D.
Associate Professor
High Res Photo

Associate Professor

Dr. Joon Y. Park is a biomedical researcher and exercise scientist joining the Department of Health, Human Performance, and Recreation, Robbins College of Health and Human Sciences. Prior to join, he was Associate Professor of Cardiovascular Research Center and Kinesiology at Temple University. In collaboration with experts in various fields, Dr. Park uses multidisciplinary innovative approaches, including microfluidics systems, -omics technology, and machine learning platform. His research program has been continuously sponsored by federal and organizational funding agencies. ( He is also passionate about STEM education across the undergraduate, graduate, and postdoctoral levels. His trainees have been awarded various national awards and funding, including NIH MARC U-STAR, Goldwater Scholarship, AHA Predoctoral & Postdoctoral fellowship. Dr. Park is involved in multiple national services as journal editor, grant reviewer, research award committee, and program working group.

Research Interests

  • Fluid shear stress-induced mitochondrial remodeling
  • Cellular mechanism of muscle memory
  • Cell-to-cell communications between muscle, vessel, and fat cells
  • EV-linked cerebrovascular and lymphatic biomarker for CTE and sports-related concussion

Current Courses Taught

  • HP5379 Research Methods

Select Publications

  • Hong SG et al., Disturbed-Flow Instigates Mitochondrial Fragmentation, Leading to Atheroprone Phenotype in Endothelial Cells, JCI Insight, 2022*
  • Shin JC et al., Unidirectional Laminar Flow-induced Endothelial Mitochondrial Remodeling Mitigates Mitochondrial Reactive Oxygen Species Production and Promotes Mitochondrial DNA Integrity in a p53-dependent manner. Redox Biol, 50:102252. doi: 10.1016/j.redox.2022.102252, 2022*
  • Meister BM et al., Healthy vs. Unhealthy Adipose Tissue Expansion: The Role of Exercise, J of Obesity and Metabolic Syndrome, 31(1): 37-50, 2022*
  • Hong SG et al., Mitochondrial and Metabolic Adaptations to Exercise-Induced Fluid Shear Stress in Endothelial Cells, Exerc Sport Sci Rev, 1:50(3):145-155, 2022*
  • Tian R et al., Unlocking the Secrets of Mitochondria in the Cardiovascular System: Path to a Cure in Heart Failure, Circulation, 140 (14): 1205-1216, 2019
  • Lee HJ et al., A cellular mechanism of muscle memory facilitates mitochondrial remodeling following resistance training, J Physiol, 596(18): 4413-4426. 2018*
  • Kim JS et al., Shear stress-induced mitochondrial biogenesis decreases the release of microparticles from endothelial cells, Am J Physiol-Heart Circ Physiol, 309(3):H425-433, 2015*
  • Kim B et al., Inhibition of Drp1-Dependent Mitochondrial Division Impairs Myogenic Differentiation, Am J Physiol Regul Integr Comp Physiol, 305(8):R927-938, 2013*
  • Wang PY et al., Increase in Oxidative Metabolism Li-Fraumeni Syndrome, N Engl J Med, 368(11):1027-1032, 2013
  • Park JY et al., p53 improves aerobic exercise capacity and augments skeletal muscle mitochondrial DNA content, Circ Res 25;105(7):705-12, 2009

*corresponding author

Education & Training

Postdoctoral fellowship, Translational Medicine Branch, NHLBI/NIH, Bethesda, MD
Ph.D., University of Maryland, College Park
M.S., Seoul National University
B.S., Seoul National University