CASPER Seminar Series presents Dr. Touradj Solouki

DateApril 4, 2014Time2:30 - 3:30 pm
LocationBRIC - Room 3160

Prof. Touradj Solouki
Department of Chemistry and Biochemistry - Baylor University

Radiofrequency Ionization coupled with Fourier Transform Ion Cyclotron Resonance Mass Spectrometry (RFI FT-ICR MS)

Enhancing sensitivity in mass spectrometry (MS) experiments largely depends on the efficient generation of ions and their detection. Ionization methods employed in MS are generally grouped into various types (e.g., ionization of gases, liquids, and solids) and a conventional approach is to cluster them into two major categories of "soft" and "hard" ionization approaches. Recently, during the process of investigating ion trajectories within high magnetic field regions of a 9.4 T superconducting magnet, we discovered that radiofrequency ionization (RFI) might allow "soft" and/or "hard" ionization of volatile and semi-volatile organic molecules for highly efficient MS analyses. RFI produces fragment and intact molecular ions under ultrahigh vacuum and MS compatible pressures. Electrons are also produced during the RFI but exact mechanism(s) of ion generation remains unknown. In this presentation, theoretical/ion trajectory results and experimental findings from RFI MS will be presented. Moreover, potential and unique advantages of RFI in modern "x-omics" MS will be discussed.

A brief Bio: Dr. Touradj Solouki is a professor of Chemistry and Biochemistry at Baylor University. He teaches a variety of graduate and undergraduate courses such as "X-omics Bioanalytical Mass Spectrometry" and "Analytical Measurements and Techniques/Quantitative Chemical Analysis". His research is focused on gas-phase ion-molecule reaction kinetics, ion dissociation mechanisms, conformational analyses, instrument development, and biomarker discovery through "X-omic" structural and tandem mass spectrometry. He completed his Bachelor’s degree at the University of Texas at Tyler, and his Ph.D. at Texas A&M University. He did a Welch undergraduate summer research at Baylor University and a Welch summer postdoctoral fellowship at Texas A&M University. He also completed a postdoctoral fellowship at the National High Magnetic Field Laboratory (NHMFL) in Florida. He then became a senior scientist at the Illinois Institute of Technology Research Institute (IITRI) and worked as a laboratory director for Chemical and Biological defense type endeavors in Chicago. Before coming to Baylor, he was a Professor of Chemistry at the University of Maine in Orono, Maine. Dr. Solouki routinely serves as a peer-reviewer for several journals in fields of biology, chemistry, environment, and physics as well as numerous funding agencies such as the NIH and NSF.

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