ENV Seminar Series - Chris Wong

DateSeptember 26, 2013Time1:00 - 1:50 pm
LocationBSB E234
DescriptionEndocrine Disrupting Chemicals, the Exposure and Their Multiple Effects on Reproductive Dysfunction In the past century the relentless advance of industrialization and technology and the consequent rapid growth of human populations have impacted on the environment in a way that is unprecedented in human history. An enormous number of synthetic chemicals with diverse structural features have been produced for industrial, medical and domestic purposes. These chemical substances, originally thought to have little or no biological toxicity, are widely used in our daily lives and are present in foods. It was not until the first World Wildlife Federation Wingspread Conference held in 1994 were concerns about the endocrine disrupting effects of these chemicals articulated. Since then, considerable numbers of studies have been conducted to reveal the health effects of endocrine disrupting chemicals (EDCs). The potential hazardous effects of EDCs on human health and ecological well-being are one of the global concerns that affect the health and propagation of human beings. Considerable amount of studies indicated that endocrine disruptions are directly linked to “the developmental basis of adult disease”, highlighting the significant effects of ED exposure to a developing organism, leading to the propensity of an individual to develop a disease or dysfunction in later life. In this talk we will provide environmental and experimental data to associate EDC exposure with reproductive disorders, in particular on the male system. The possible effects on hypothalamus-pituitary-gonadal axis, testicular signaling and steroidogenesis will be discussed.
Publisherzzz (Old) Environmental Science
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