|Date||April 17, 2019||Time||4:00 - 5:00 pm|
|Location||Baylor Sciences Building, Room E.125|
Orlando Auciello, Ph.D.
Science and Technology of Multifunctional/Biocompatible Ultrananocrystalline Diamond (UNCDTM) to Microcrystalline Diamond (MCD) Coatings and Applications to a New Generation of High-Tech Electronics and Implantable Medical Devices
New paradigms in the research and development of nanocarbon thin films are providing the bases for new physics, materials science, chemistry, and biological processes, impacting a new generation of multifunctional high-tech and biomedical devices. This talk will focus on discussing the science and technology of a new paradigm material named ultrananocrystalline diamond (UNCDTM), nanocrystalline diamond (NCD) and microcrystalline diamond (MCD) all in thin film form and their integration into new generations of high-tech and external and implantable medical devices, as described below: UNCD films co-developed and patented by O. Auciello and colleagues are synthesized by novel microwave plasma chemical vapor deposition and hot filament chemical vapor deposition techniques using an Ar-rich/CH4 chemistry that produces diamond films with the smallest gran size demonstrated today (2-5 nm). The fundamental science underlying the synthesis and properties of the UNCD films and applications to devices will be discussed. The UNCD films exhibit the lowest friction coefficient (0.02-0.04) compared with metals (≥ 0.5) currently used in many prostheses (e.g., hips, knees), electrically conductive UNCD coatings with nitrogen in grain boundaries can enable a new generation of neural electrodes, UNCD coatings are extremely biocompatible, and have been demonstrated to provide superior scaffolds for embryonic cell growth and differentiation. Original Biomedical Implants (OBI-USA) and OBI-México, founded by Auciello and colleagues, are developing new generations of high-tech diamond-based electronics and implantable medical devices based on multifunctional/biocompatible UNCD to MCD coatings, described in order of less to highest development until now, namely: a) new generation of high-power diamond film-based electronics; b) Brain neurons functionalized UNCD-coated polymer with tailored stiffness, enabling next generation less invasive electrodes for neural stimulation c) UNCD-based MEMS cantilevers demonstrated as high sensitivity biosensors; d) UNCD-based MEMS cantilevers powered by biting heart cells to power new generation defibrillator/pacemaker, eliminating battery power; e) new generation of Li-ion batteries with ≥ 10x longer life and safer, using UNCD-based electrodes, membranes and inner wall battery case, enabling next generation defibrillator/pacemakers and implantable and external power generation devices with order of magnitude longer battery powered life; f) new generation of implantable prostheses (e.g., dental implants (in clinical trials in humans), hips, knees, stents and more) coated with UNCD, eliminating failure of current metal-based implants due to synergistic mechanical wear or blood interaction / chemical corrosion by body fluids; g) Integrated UNCD-coated magnet outside the eye, creating magnetic field to attract biocompatible superparamagnetic FeO2 nanoparticles injected inside the eye to push detached retina to place, enabling revolutionary retina reattachment; h) A key medical device where UNCD coating has made an impact is a UNCD-coated silicon based microchip implantable inside the eye as a key component of the artificial retina to return partial vision to people blinded by genetically-induced degeneration of photoreceptors (a device named Argus II is currently in the market by Second Sight, returning partial vision to people blinded by retinitis picmentosa).
|Publisher||Department of Physics|
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