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Instrumentation

 

 

Synapt G2-S

Waters Synapt G2-S HDMS

High resolution mass spectra (over 40,000) can be obtained in concert with with gas-phase ion mobility separations. Samples introduction may be accomplished via direct infusion or by a nano Acquity-UPLC system. Data generated in any of the Waters mass spectrometers present in the center can be analyzed in a dedicated processing computer that includes Protein Global Lynx Server (PLGS) intended for bottom up proteomic analysis.

 

Synapt

Waters Synapt HDMS

High resolution mass spectra (up to 17,000) can be obtained using a Waters Synapt HDMS. Ions can be separated in the Synapt mass spectrometer by quadrupole time of flight mass spectrometry or/and by gas-phase ion mobility separation. Samples can only be introduced into the Synapt by direct infusion.

 

Xevo TQS

Waters Xevo TQ-S

Nominal mass MS and MS/MS data can be obtained in a triple quadrupole Xevo TQ-S mass spectrometer. Samples can be introduced to the TQ-S by direct infusion or by an attached Acquity-UPLC system.

 

Orbitrap

Thermo Orbitrap Discovery (Room E156R)

Direct infusion, high resolution mass spectra (up to 30,000) can be obtained using ESI, APCI/APPI and nano-ESI. A dedicated processing computer that includes Proteome Discoverer (proteomic bottom up analysis) and Sieve (identification of samples with statistical inter-sample differences) is available in E.156.R.

 

Thermo Orbitrap Q-exactive Focus

High resolution mass spectra (up to 70,000) can be obtained via direct infusion (ESI, APCI/APPI, or nano-ESI) or via an Accela analytical-flow LC system. A dedicated processing computer that includes Proteome Discoverer (proteomic bottom up analysis) and Sieve (identification of samples with statistical inter-sample differences) is available

 

DSQ

Thermo DSQ

Electron ionization (EI) mass spectra can be obtained using a Thermo Scientific DSQ II. Sample introduction by direct insertion probe or by using the attached Focus gas chromatograph.

 

Agilent 7900

Agilent ICP-MS 7900

Trace-level quantitative analysis of metals in samples at part-per-trillions concentration levels.

 

Agilent 6420

Agilent LC-MS/MS 6420

ESI via for direct infusion or an Agilent 1260 LC system.

 



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