The cardiovascular group is comprised of multidisciplinary teams striving for research excellence. The long term goal of the cardiovascular group is to develop novel therapeutics based on a thorough understanding of relevant genes, including the expression, control, and regulation of those genes as they relate to the pathology of diseases. Major research areas include role of renin-angiotensin system in cardiovascular diseases, brain trauma, immunosuppressive drug-induced hypertension, pregnancy-induced hypertension, the regulation of coronary and retinal arteriolar function in health, cardiac fibrosis. Many of the researchers combine basic and clinical research to include translational components pertaining to human diseases. Although diverse in topic areas and model systems, members of the cardiovascular research teams are actively engaged in collaborations among labs both within and outside the institute. A highly congenial atmosphere provides excellent educational opportunities for students and fellows to receive research training in these labs.