Organic Chemistry

  • Research - Analogues of Benzene
  • Research - Combretastatin Dinitrogen-Substituted-Stilbene
  • Research - Structural Interrogation of Benzosuberene-based Inhibitors of Tubulin Polymerization
  • Research - Synthesis and Biochemical Evaluation of Benzoylbenzophenone
  • Research - Mechanistic considerations in the synthesis of 2-aryl-indole analogues
  • Research -  Unsaturated Acylammonium Salts as Dienophiles
  • Research - Regio- Stereopspecific Synthesis
  • Research - Synthesis and Application of C2-Chiral Phosohinines

Charles M. Garner
Research Group - Research in my group centers around the synthesis and analysis of chiral organic compounds. We are working to improve catalytic asymmetric processes by developing new chiral ligands for transition metal catalysts.

Robert Kane
Research Group - Dr. Kane is the director of the Center for Drug Discovery and the Institute for Biomedical Studies.

Caleb D. Martin
Research Group - Boron-Based Organic Materials and Catalysis

Research in the Martin group is focused on understanding new avenues in organoboron chemistry. Our research is focused on developing new bonding arrangements around the boron centre and subsequently exploring the chemistry of these novel compounds. The desired compounds will have unusual properties and be examined for their utility in optoelectronics, Lewis acid mediated catalysis and small molecule activation reactions. Our research interests span organic, organometallic and materials chemistry.

Kevin G. Pinney
Research Group - A primary focus of the research efforts of the Pinney Group lies in the total synthesis of structurally challenging and biologically relevant and interesting natural and non-natural products.

Daniel Romo
Research Group - At the heart of our research interests is the chemistry and biology of natural products. These are unique and often structurally complex molecules that are designed to interact in highly specific ways with various cellular receptors and by homology those found in humans. Thus, all our projects begin with natural products and encompass: (i) development of novel synthetic strategies enabling access to derivatives in route to the natural product through 'bioactivity-guided retrosynthesis' (ii) discovery of novel reactivity of unsaturated acylammonium salts for organocascade processes with applications to natural products (iii) microscale, chemo- and site-selective functionalization of natural products for inquiries into cell biology including cellular target identification (iv) mass spectrometry based-profiling of the cancer proteome with natural product probes (v) CO2 fixation for beta-lactone synthesis and natural product derivatization.

John L Wood
Research Group - Starting with Wohler's total synthesis of urea almost two centuries ago, the chemical synthesis of naturally occurring molecules has inspired creativity and led chemists to make important advances in areas ranging from drug development to materials science. Unlike many fields where the target of research efforts is defined by the researcher - allowing convenient adjustment to match shortfalls in capability - the goal in natural products synthesis is predefined by nature and the challenge is to develop methods and strategies that allow for the solution of a precise problem; however, for most molecules there is an infinite number of conceivable syntheses. Thus, these intriguing products from nature represent a virtually limitless source of inspiration to chemists; no matter how many times they are targeted for synthesis or successfully prepared, they continue to fuel creativity and scientific achievement in our field and beyond.".