Karolina Palucka, M.D., Ph.D.
|
|
Dr. A. Karolina Palucka earned her M.D. in 1988 from Warsaw Medical Academy in Poland. She went on to complete her Ph.D. in Hematology and Immunology in 1993 at the Karolinska Institute in Stockholm, Sweden. Dr. Palucka is an Investigator at the Baylor Institute for Immunology Research in Dallas, where she began in 1998 as a Senior Research Associate. She holds the Michael A.E. Ramsay Chair for Cancer Immunology Research. She also oversees the Flow Cytometry Core and the GMP Cell Core. In August 2005, she was appointed to an Adjunct Professorship in Biomedical Studies at Baylor, Waco. Dr. Palucka and her team focus on understanding how the human immune system works and how it may be manipulated to fight cancer. She also leads a project to develop a mouse model of the human immune system, which is being used to study human tumors and how they influence dendritic cell function. These ‘humanized' mice are also being used to develop improved vaccine strategies.
Recent Publications
•Paczesny, S., Shi, H., Saito, H., Mannoni, P., Fay, J., Banchereau, J., and Palucka, A.K. (2005). Measuring melanoma-specific CTLs elicited by dendritic cell vaccines with a tumor inhibition assay in vitro. J. Immunotherapy. 28 :148-157.
•Palucka, A.K., Dhodapkar, M., Paczesny, S., Ueno, H., Fay, J., and Banchereau, J. (2005). Boosting vaccinations with peptide-pulsed CD34+ progenitor derived dendritic cells can expand long-lived melanoma peptide-specific CD8+T cells in patients with metastatic melanoma. J. Immunotherapy. 28 :158-168.
•Palucka, A.K., Blanck, J.-P., Bennett, L., Pascual, V., and Banchereau, J. (2005). Cross-regulation of TNF and IFN-a in autoimmune diseases. PNAS. 102:3372-7.
•Rolland, A., Guyon, L., Gill, M., Cai, Y-H, Banchereau, J., McClain, K., and Palucka, A.K. (2005). Increased blood myeloid dendritic cells and DC-poietins in langerhans cell histiocytosis. J. Immunol. 174 :3067-71.
•Palucka, A.K., Connolly, J., Ueno, H., Kohl, J., Paczesny, S., Dhodapkar, M., Fay, J., and Banchereau. Spontaneous proliferation and type 2 cytokine secretion by CD4+ T cells in patients with metastatic melanoma vaccinated with antigen-pulsed dendritic cells. J. Clin. Immunol. 25(3):288-295.
To contact Dr. Palucka, feel free to email her at karolinp@baylorhealth.edu.
