Course DescriptionsNote: These courses supplement the main courses already given in the Graduate Bulletin. The student also will take regular courses from the two disciplines: biological sciences and chemistry. The courses listed here give more detail than those listed in the Graduate Bulletin. The numbers in parentheses following course descriptions indicate the number of lecture and laboratory hours per week, respectively.
Prerequisite(S): Enrollment In Graduate Program
Students are required to register for the weekly seminar (a forum for outside speakers, presentation of student research and discussion of selected topics) and to present papers. No more than three (3) semester hours may be counted on a master's degree and no more than six (6) may be counted on a Ph.D. (1-0) Maximum 6 semester hours.
Current Concepts In Immunology
Prerequisite(S): BIO 4301 Or 5301
Lectures developing technology and trends in immunology particularly those elements that relate to medical and research applications of immunology. The annual reviews of immunology and recent literature, as well as the fundamental problems being addressed in immunology research by staff, will serve as resource information. New concepts and approaches to vaccine production, diagnostic procedures, and immunotherapy, immunomodulation, gene family antibody synthesis, and cell-cell and cellhumoral agent interactions will be surveyed. (3-0)
Biochemical And Molecular Genetics
Prerequisite(S): Previous Or Concurrent Enrollment In CHE 4341, 4342 Or 5348, Or Consent Of Instructor
Biochemical and molecular aspects of the inborn errors of human metabolism. Particular attention will focus on laboratory methods employed for the detection of hereditary disease, including organic and amino acid analysis, and routine metabolic screening. Molecular studies will include common techniques such as DNA and RNA isolation and purification; electrophoresis of nucleic acids; preparation of DNA libraries; and Western, Northern and Southern analysis. (3-0)
Structure And Function Of Muscle
Prerequisite(S): BIO 4307 And CHE 4341
Fine structure, physiology, biochemistry and biophysics of all muscle types from invertebrates through vertebrates. (3-0)
Biotechnology And Cell Biomedicine
Prerequisite(S): Enrollment In Biology, Chemistry Or Biomedical Studies Program. BIO 4306 Preferred But Not Required.
Interdisciplinary course that covers basic mechanisms of molecular biology and genetics along with rigorous presentation of state-of-theart research methodology. Utilization of DNA/ RNA/protein regulation technology in biomedical and clinical applications. (3-0)
Molecular Biology Of The Cell
Prerequisites: BIO 4307
Advanced topics in cell biology. Cell division, replication and recombination of DNA and mutations and repair of DNA will be reviewed. Application of restriction enzymes, recombinant DNA technology and sequencing of DNA to study molecular architecture of the cell will be overviewed. (3-0)
Studies In Intermediary Metabolism
Prerequisite(S): CHE 4341 Or Consent Of Instructor
Investigation of the interrelationships of energy utilizing and producing metabolic pathways. Consideration will be given to glycolysis, Kreb's cycle, oxidative pathways of fatty acids and amino acids, and the pathways of lipid and sterol formation, in addition to various aspects of gluconeogenesis and the pentosephosphate shunt. (3-0)
Prerequisite(S): Previous Or Concurrent Enrollment In CHE 4341, 4342 Or 5348
Common techniques employed in hospital clinical laboratories, including determination of small molecules such as glucose, lactate and pyruvate; determination of acid/base balance and disturbances; quantification of electrolytes; and the measurement of routine hepatic enzymes such as LDH, SGOT and SGPT. (2-3)
Special Techniques In Immunology
Prerequisite(S): CHE 4341 And 4342 Or Consent Of Instructor
Immune responses of vertebrate animals, including immunochemistry and molecular genetics. Cellular responses will be analyzed by conventional skin tests, in vitro correlates of delayed-type hypersensitivity, histology and laser-activated cell sorting. (2-6)
Prerequisite(S): BIO 4401, CHE 4341 Or Consent Of Instructor
Basic and clinical virology with a major emphasis on the characteristics of major animal viruses, viral infections of humans and mechanisms by which viruses infect or transform cells. Laboratory techniques will stress basic methods used in animal viral research and laboratory diagnosis of viral infections, including tissue culture, plaque titration, ultra-centrifugation, immunofluorescence, nucleic acid probes and standard serologic assays. (3-3)
Microbiology, Virology, And Infectious Diseases Ii
Prerequisite(S): CHE 4341 And BIO 4401
Pathogenic microbiology, host-parasite interactions, immunology, virology, basic microbiology, antimicrobial agents. (3-3)
Prerequisite(S): Consent Of StudentS Dissertation Or Advisory Committee
Directed research for those students who have not yet passed the Ph.D. preliminary examination and who have not yet selected a Ph.D. dissertation topic. May be repeated for no more than twelve (12) semester hours of credit. (Not to be counted on master's degree.) (0-9) or (3-0) Maximum 12 semester hours.
Prerequisite(S): Consent Of StudentS Thesis Committee Or A Minimum Of Twelve (12) Hours Of Graduate Work
A minimum of six (6) semester hours is required. Maximum 10 semester hours.
Special Problems In Biomedical Studies
Prerequisite(S): Consent Of StudentS Dissertation Committee
Selected topics in biomedical studies. May be repeated with change in content. No more than six (6) semester hours total credit allowed. Maximum 6 semester hours.
Prerequisite(S): Consent Of The Student's Dissertation Committee And Admission To Candidacy.
A minimum of twelve (12) semester hours is required. Maximum 17 semester hours.